01WORKING PROTOTYPE
FASTQ validation
Check four-line records, sequence characters, separators, and matching sequence and quality lengths.
See how validation works →BIOINFORMATICS FOR PUBLIC HEALTH
From raw reads to
clearer results.
Kmeggie+ is building lightweight sequencing quality-control software around the realities of African laboratories.
Early development · Working browser-based FASTQ validation and QC reporting prototype
224
bioinformaticians are estimated to be immediately needed across African public-health genomics facilities.
Read the 2025 Nature Medicine source ↗PRODUCT STATUS
What works today—and what comes next.
Each capability is labelled by its current stage so evaluators can separate working software from the roadmap.
02BROWSER PROTOTYPE
Automated QC reporting
Review quality, composition, length, duplicate, and N-content summaries; export a readable report.
Explore QC reporting →
03IN DEVELOPMENT
Production CLI workflow
Kmeggie+ is developing a production command-line workflow and formal performance benchmarks. Pipeline orchestration remains on the roadmap.
View the roadmap →THE PROBLEM WE ARE ADDRESSING
Sequencing capacity is growing. Confidence in the data must grow with it.
Producing a FASTQ file is not the same as producing trustworthy genomic evidence.
Africa’s sequencing capacity is expanding, but workforce and analytical infrastructure have not grown at the same pace. Kmeggie+ focuses on the critical first checkpoint: making raw FASTQ validation and quality-control findings easier to run and understand.
Read the full problem & solution →BUILT FOR
Start with the laboratory context.
Select your perspective
FOR PUBLIC-HEALTH LABS
A clearer first check in the daily workflow.
Validate FASTQ structure, examine quality signals, and keep local files on the laboratory device.
See the public-health lab solution →
FOR GENOMICS RESEARCHERS
Transparent measurements before deeper analysis.
Review base quality, composition, read lengths, and method notes before deciding what to investigate next.
See the researcher solution →
FOR DIAGNOSTIC LABS
Practical QC with clear boundaries.
Explore a research prototype designed around traceable checks. Clinical validation and diagnostic deployment remain future work.
See the diagnostic lab pathway →LOW-BANDWIDTH & OFFLINE-FIRST
Keep the analysis close to the lab.
Kmeggie+ is being shaped as a lightweight, self-hosted toolkit. The browser prototype analyses files on the device; your sequencing data is not uploaded to a server.
Read the quickstartLIVE SAMPLE WALKTHROUGH
Follow a sequencing file.
Choose a synthetic sample and see why file validity and read quality are separate questions.
Step 1 of 4
Synthetic demonstration data. The walkthrough uses the prototype’s local analysis engine and is not a clinical assessment.
EXPLORE KMEGGIE+
The context. The workflow. The direction.
Select an image to enlarge it. Use Previous and Next to explore.
A proposed workflow
A path to accessROADMAP
What is next.
Planned capabilities are shown separately from the working prototypes.
NOWFASTQ validation
Working browser prototype
NOWAutomated QC reports
Interactive browser report and export
NEXTProduction CLI workflow
Command-line workflow and formal benchmarks in development
PLANNEDPipeline orchestration
Institutional reporting and multi-laboratory workflows
COMING SOONVeritas AI — Smart Variant Triage
First-pass variant review after QC. Not live yet.
Coming soon
Veritas AI — Smart Variant Triage
After a sample passes QC, someone still has to look through the results and decide what matters.
We are exploring an AI-assisted feature for first-pass variant review after QC. It is a roadmap concept, not a current product capability or a replacement for specialist interpretation.
This is not live yet. Development remains focused on the QC prototype, production CLI workflow and formal benchmarks.
PILOT INTEREST
Help us test Kmeggie+ against real laboratory conditions.
We are preparing structured discovery and pilot work with public-health and genomics laboratories. No signed pilot or institutional endorsement is claimed.