Kmeggie+SEQUENCING, SIMPLIFIED
THE SEQUENCING WORKBENCH

Know your reads.

Inspect a FASTQ file, review its quality, and take the report with you.

I. SPECIMEN INPUT

Start with a FASTQ file

Single-end reads · Phred+33 quality scores

Just exploring?500 synthetic reads
II. ANALYSIS RECORD

Preparing sample report…

SYNTHETIC SAMPLELocal analysis
Analyzing readsPreparing the demonstration dataset.

Quality across the read

Mean Phred score at each base position

Mean quality

Prototype guide: Q ≥ 30 pass · Q 20–29 review · Q < 20 low quality

Validation checks

A quick check before your next step

Flags guide review. They do not determine whether a sample is suitable for clinical use.
Analysis details & interpretation +

All reads in an accepted file are analyzed. This prototype supports four-line, single-end FASTQ with A/C/G/T/N bases and Phred+33 scores. Limits: 50 MB input, 100 MB decompressed, 200,000 reads, 100,000 bases per read. Files above a limit are rejected rather than sampled.

Mean quality is the arithmetic mean of all base scores. Q30 is the share of bases with a score of at least 30. N content flags: ≤1% pass, ≤5% review, >5% low quality. Exact duplicate fraction = (reads − unique sequences) / reads; descriptive only. For long reads, charts group adjacent positions into at most 600 points; checks still use every position. These are simplified prototype rules, not FastQC-equivalent checks. Adapter detection, paired-end validation and classification are not included.

This web prototype is independent of the Kmeggie+ CLI. It is not a validated diagnostic tool. Reports are kept only in this open tab unless exported.

Methods & limits